Application Note - CTC Characterization via FISH Probes

Cytogenetic Monitoring of Cancer Progression in Circulating Tumor Cells
Utilizing the IsoFlux System and GenASIs Spectral Imaging Technology

  • Circulating tumor cells (CTCs) have shown promise as a clinically-relevant sample for monitoring the genetic variation of cancer progression
  • Fluorescence in situ hybridization (FISH) is a single-cell approach to understanding patient-specific molecular profiles of disease
  • FISH analysis of CTCs offers a less invasive method for tracking disease progression at the genome level
  • The IsoFlux System (Fluxion Biosciences) provides a robust method for accessing CTCs and optimizing use in FISH assays
  • GenASIs (Applied Spectral Imaging) provides a cutting-edge hardware and software platform for high resolution imaging of FISH slides

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