Use of porous hydrophobic polymers filled and coated with water immiscible hydrophobic liquids for protein- and cell-repellent surfaces

Publication number US20140087173 A1
Publication type Application
Application number US 14/031,912
Publication date Mar 27, 2014
Filing date Sep 19, 2013
Priority date Sep 20, 2012
Also published as EP2711417A1
Inventors Erica Boles, Pavel Levkin, Ursula Obst, Thomas Schwartz, Junshen Li
Original Assignee Karlsruher Institut Fur Technologie

 

Abstract
 
The present invention relates to a substrate with a solid support coated with a porous hydrophobic polymer layer or film, wherein said polymer layer or film is coated with a water-immiscible hydrophobic liquid forming a stable film on the polymer surface. The present invention further relates to a method of forming a protein- and cell-repellent surface, comprising the steps of providing a substrate with a solid support coated with a porous hydrophobic polymer layer or film, and applying a water-immiscible hydrophobic liquid to said porous hydrophobic polymer layer or film, a respective method of preventing the formation of biofilms, adhesion of cells and bacteria, and/or migration of cells and bacteria on a surface, as well as the use of a porous hydrophobic polymer layer or film that is coated with a water-immiscible hydrophobic liquid for forming a protein-, cell- and bacteria-repellent surface.

 

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